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Central Venous Catheters for Dialysis (CVCDs)

Catheter Related Bloodstream Infection (CRBSI)

Personal Data:

  • Born September 22, 1945, Kansas City, MO
    Married, 2 children

Position Titles:

  • Chairman of the Board of Directors and Director of R&D
    HemoCleanse, Inc. and Ash Access Technology, Inc.
  • Medical Director and Director of R&D
    Renal Solutions, Inc.
  • Adjunct Associate Professor,
    Purdue University, West Lafayette
  • Clinical Associate, 
    Indiana University Medical Center, Indianapolis.
  • Director, 
    Dialysis Center for Greater Lafayette and GLHS Hospital Staff Member.
  • Member and Nephrologist,
    Arnett Clinic, Lafayette, Indiana. 

Position Responsibilities:

As Chairman of the Board: Presides over all Board of Directors meetings. Member of Executive Management Committee.  As Medical Director: Provides leadership and direction to all R&D activities. Serves as monitor and investigator in clinical trials of devices. Principal contact for FDA, patent office, and NIH matters.

As a Director of the Dialysis Center for Greater Lafayette, supervises and helps to administrate four separate dialysis clinics operated by GLHS of Lafayette. As Staff Member of GLHS Hospitals provides Nephrology consultation and directs dialysis treatments.

As Member and Nephrologist of Arnett Clinic provides consultation and patient care within the Nephrology Department.

At Purdue University and Indiana University teaches courses for engineers and visiting physicians and assists in education within the Lafayette Center for Medical Education of physicians and medical students of the IUMC Extension at Purdue University.

Society Positions

Founder of American Society for Diagnostic and Interventional Nephrology, 2001, President, then Past President

President, American Society for Artificial Internal Organs, 2005-2006

Secretary-Treasurer of the International Federation of Artificial Organs, 2008

Member of ASN, ISPD, ISHD, AASLD, APA, AMA, ACP.

Education

B.A., Physics, 1967, Northwestern University

M.D., Medicine, 1971, Kansas University Medical School

Postdoctoral Fellow, Physiology, 1972-73, Indiana University Medical School

Residency in Internal Medicine, 1971-74, Indiana University Medical School

Fellowship in Nephrology, 1974-75, Indiana University Medical School

Business/Research Experience

1989 to Present      HemoCleanse, Inc., Lafayette, Indiana

Chairman of the Board of Directors; Director of Research and Development; Medical Director

HemoCleanse, Inc. was established to manufacture and market devices for the treatment of liver failure and drug overdose.

1983 to Present      Ash Medical Systems, Inc. (now Ash Access Technology), Lafayette, Indiana

Chairman of the Board of Directors; Director of Research and Development; Medical Director

Ash Access Technology, Inc. was formed to design and produce body access devices to improve dialysis access and improve chemical sampling of the body.

1980 to Present      Purdue University; West Lafayette, Indiana

Adjunct Associate Professor, Comparative Medicine, Department of Veterinary Medicine

1975 to Present      Arnett Clinic; Lafayette, Indiana

Practicing physician, Internal Medicine with specialization in Nephrology

1975 to Present      St. Elizabeth Hospital Medical Center and Home Hospital; Lafayette, Indiana (“Greater Lafayette Health Services”)

Director, Dialysis Services

1975 to 1983      Purdue University; West Lafayette, Indiana

Research Associate and Director, Hemodialysis Laboratory, Institute for Interdisciplinary Engineering Studies

Affiliations and Honors

Alpha Omega Alpha, 1971, University of Kansas

William Bailey Award for Research in Pathology, 1971, University of Kansas

Board Certification, American Board of Internal Medicine, 1976

Board Certification, American Board of Internal Medicine, Nephrology Section, 1978

Fellow, American College of Physicians, 1981

Recipient of Elizabethan Award, St. Elizabeth Hospital Medical Center, Lafayette, Indiana, 1991

Listed in The Best Doctors in American, 1999 Edition

Member, Board of Directors: American Society for Artificial Internal Organs, 2000-present  (Program Chairman, 2003; Secretary-Treasurer 2004)

Member, Board of Directors: International Society for Apheresis, 2000-present

Founding Member and Editor in Chief:  American Society of Diagnostic and Interventional Nephrology, 2000-present  (President, 2003)

Member: ASAIO, AASLD, ASN, ACP, ISAO, ISPD, ASDIN

Outstanding Abstract Award for Best Hemodialysis Abstract, 20th Annual Convention on Dialysis, Symposium on Home Hemodialysis, February 2000


PATENTS

Australian Patent No. 2002213191 “DEVICES AND METHODS FOR BODY FLUID FLOW CONTROL IN EXTRACORPOREAL FLUID TREATMENTS. by SR Ash, Assignee Renal Solutions, 2006

U.S. Patents (partial list)

U.S. Patent No. 6,264,680. “APPARATUSES AND PROCESSES FOR WHOLE-BODY HYPERTHERMIA” by SR Ash, Assignee: ViaCirQ, Inc., July 24, 2001.

U.S. Provisional Patent Application. “CATHETER INTRODUCER HAVING AN EXPANDABLE TIP.” by AB Korkor and SR Ash, filed June 2001.

U.S. Provisional Patent Application. “A CATHETER LOCK SOLUTION INCLUDING A PHOTO-OXIDANT” by SR Ash, filed May 10, 2000.

U.S. Provisional Patent Application. “USE OF MAGNETIC PARTICLES IN A FLUID FOR MIXING AND BLOOD LEAK DETECTION” by F Friedlaender and SR Ash, filed May 5, 2000.

U.S. Patent No. 6,348,162 “Starting dialysate composition for use as an initial dialysate” By SR Ash

U.S. Patent No. 6,409,699  “CONTINUOUS FLOW-THROUGH PERITONEAL DIALYSIS (CFPD) METHOD WITH CONTROL OF INTRA PERITONEAL PRESSURE” by SR Ash, filed June 28, 1999, issued Feb, 2002.

U.S. Patent No. 6,190,349  “Splittable multiple catheter assembly and methods for inserting the same” by SR Ash, AJ Madison, and TM Schweikert

U.S. Patent No. 6,042,561. “NON-INTRAVASCULAR INFUSION ACCESS DEVICE” by SR Ash and EM Janle, March 28, 2000.

U.S. Patent No 5,947,953. “SPLITTABLE MULTIPLE CATHETER ASSEMBLY AND METHODS OF INSERTING THE SAME” by SR Ash, AJ Madison, and TM Schweikert, September 7, 1999.

U.S. Patent No. 5,919,369. “HEMOFILTRATION AND PLASMAFILTRATION DEVICES AND METHODS” by SR Ash, July 6, 1999.

U.S. Patent No. 5,906,978. “METHOD OF IRON DELIVERY TO A PATIENT BY TRANSFER FROM DIALYSATE” by SR Ash, May 25, 1999.

U.S. Patent Application 09/237,476. “SILICA-CONTAINING SORBENT SUSPENSIONS AND TREATMENTS USING SAME” by SR Ash, filed January 26, 1999.

U.S. Patent Application 60/097,777. “METHODS OF ENHANCING CATHETER PATENCY USING A CITRATE SALT CATHETER LOCK SOLUTION” by SR Ash, filed August 25, 1998.

U.S. Patent No. 5,536,412. “Hemofiltration and Plasmafiltration Devices and Methods” by SR Ash, July 16, 1996.

Des. 370,531. “Peritoneal Dialysis Catheter Implanter” by SR Ash and JA Navis, June 4, 1996.

U.S. Patent No. 5,476,444. “Specialized Perfusion Protocol for Whole-Body Hyperthermia” by NG Keeling, SR Ash, RB Truitt, and JA Guzman, December 19, 1995.

U.S. Patent No. 5,322,519. “Foldable Catheter for Peritoneal Dialysis” by SR Ash, June 21, 1994.

U.S. Patent No. 5,277,820. "Device and Methods for Extracorporeal Blood Treatment" by SR Ash, January 11, 1994.

U.S. Patent Application. Serial No. 07/940,546, "APPARATUS FOR WHOLE BODY HYPERTHERMIA", Filed September 4,1992 and allowed on March 8, 1994.

U.S. Patent No. 5,002,054. "Interstitial Filtration and Collection Device and Method for Long-Term Monitoring of Physiological Constituents of the Body" by SR Ash and EM Janle, March 26, 1991.

U.S. Patent No. 4,995,268. "Method and Apparatus for Determining a Rate of Flow of Blood for an Extracorporeal Blood Therapy Instrument" by SR Ash and TG Echard, February 26, 1991.

U.S. Patent No.4,914,819. "Eating Utensil for Indicating When Food May Be Eaten Therewith and a Method For Using the Utensil" by SR Ash, April 10, 1990.

U.S. Patent No. 4,854,322. "Capillary Filtration and Collection Device for Long-Term Monitoring of Blood Constituents" by SR Ash and EM Janle-Swain, August 8, 1989.

U.S. Patent No. 4,777,953. "Capillary Filtration and Collection Device and Method for Long Term Monitoring of Blood Constituents" by SR Ash and EM Janle-Swain, October 18, 1988.

U.S. Patent No. 4,661,246. "Dialysis Instrument with Dialysate Side Pump for Moving Body Fluids" by SR Ash, April 28, 1987.

U.S. Patent No. 4,581,141. "Dialysis Material and Method for Removing Uremic Substances" by SR Ash, April 8, 1986.

U.S. Patent No. 4,559,039. "Permanently Placed Transcutaneous Access Device to Blood Vessels" by SR Ash and GM Kaufman, December 17, 1985.

U.S. Patent No. 4,498,902. "Catheter Guide" by SR Ash, GC Wolf and R Bloch, February 12, 1985.

U.S. Patent No. 4,413,988. "Short-Tubing Set Gravity Powered Peritoneal Cycler" by HE Handt and SR Ash, November 8, 1983.

U.S. Patent No. 4,403,984. "System for Demand-Based Administration of Insulin" by SR Ash and MP Loeb, September 13, 1983.

U.S. Patent No. 4,402,694. "Body Cavity Access Device Containing a Hormone Source" by SR Ash and MP Loeb, September 6, 1983.

U.S. Patent No. 4,387,777. "Calorie Counting Method and Apparatus" by SR Ash, June 14, 1983.

U.S. Patent No. 4,368,737. "Implantable Catheter" by SR Ash, January 18, 1983.

U.S. Patent No. 4,348,283. “Reciprocating Dialyzer Having Spacers” by SR Ash, September 7, 1982.

U.S. Patent No. 4,071,444. "Portable Chemical Reactor for Use as an Artificial Kidney" by SR Ash, PG Wilcox and DP Kessler, January 31, 1978.


Journal Publications, Published Abstracts, Textbook Chapters

Sorbent Based Dialysis Systems – BioLogic-HD System, HemoCleanse-SHD System

Sinclair A, Babbs CF, Griffin DD and Ash SR. Roux-Y intestinal bypass for administration of sorbents in uremia. Kidney Int Suppl 13(88):S153-S159, 1978.

Sinclair A, Griffin DD, Voreis and Ash SR. Sorbent binding of urea and creatinine in a Roux-Y intestinal segment. Clin Nephrol 11(2):97-104, 1979.

Ash SR, Barile RG, Thornhill JA, Sherman JD, and Wang N-HL. In vivo evaluation of calcium-loaded zeolites and urease for urea removal in hemodialysis. Trans Am Soc Artif Inter Organs 26:111-115, 1980.

Wang N-HL, Kessler DP and Ash SR. Mass transfer characteristics of a sorbent-based reciprocating dialyzer. Chem. Eng. Commun 5(5):347-365, 1980.

Ash SR, Barile RG, Wilcox PG, Wright DL, Thornhill JA, Dhein CR, Kessler DP, and Wang N-HL. The sorbent suspension reciprocating dialyzer: a device with minimal sorbent saturation. ASAIO J 4(1):28-40, 1981.

Barile RG, Wang N-HL, Blake DE, Belcastro PF, Gupta S, Regnier FE, Thornhill JA, Kessler DP, and Ash SR. A reciprocating, single-needle hemodialyzer with bidirectional flow of sorbent suspension. Artif Organs 6(3):267-279, 1982.

Badylak S, Ash SR, Thornhill JA, Carr DJ. Doppler ultrasonic detection of particulate release during hemodialysis with cellulose hollow-fiber and sorbent suspension reciprocating dialyzers. Artif Organs 8(2):220-223, 1984.

Davidson GW, Ash SR, et al. Assessment of biomaterials as components of a reciprocating dialyser during canine dialysis. Biomaterials 5(4):227-233, 1984.

Ash SR, Barile RG, Wilcox PG, Wright DL, Thornhill JA, Dhein CR, Kessler DP and Wang N-HL. The sorbent suspension reciprocating dialyzer: a device with minimal sorbent saturation. ASAIO J 4:28-40, 1984.

Winchester JF and Ash SR. Hemoperfusion for uremia: past, present, future. Kidney Int Suppl 17:S127-S130, 1985.

Ash RS, Carr DJ, Baker K, Schultz TW and Reynolds LO. Automatic priming, blood flow control, and rinsing during single access hemodialysis. Trans Am Soc Artif Inter Organs 31:499-503, 1985.

Ash SR, Carr DJ, and Blake DE. Sorbent chemicals in hemodialysis and medicine. Proc Materials Research Society on Biomedical Materials Boston, 1987.

Ash SR, Baker K, Blake DE, Carr DJ, Echard TG, Sweeney KD, Handt AE and Wimberly AL. Clinical trials of the BioLogic-HT - automated single access sorbent-based dialysis. ASAIO Trans 33(3):524-531, 1987.

Ash SR, Blake DE, Carr DJ, Baker K and Echard TG, The BioLogic-HD: hemodialysis simplified. Proc Intl Symposium Artif Organs pp. 263-277, 1986.

Koszuta JJ, Carter JM and Ash SR. Effect of ethanol perfusion on creatinine removal in a Roux-Y intestinal segment. Intl J Artif Organs 14(7):417-423, 1991.

Ash SR, Carr DJ, Blake DE, Truitt RB. Simpler, safer, more automated equipment for night-time home hemodialysis. PDI 19; Suppl 1: S87, 1999.

Ash SR, Carr DJ, Harker KD, Truitt RB, Korkor AB. Simple, safe, single-lumen system for long duration dialysis. Blood Purif 18:74, 2000.

Ash SR, Carr DJ, Harker KD, Truitt RB, Korkor AB. Simpler, safer, more-automated equipment for nighttime home hemodialysis. PDI 20 (Suppl 1):S101, 2000.

Ash SR, Carr DJ, Harker K, Truitt RB, Korkor A. Every-other night hemodialysis (QOHD) with plate dialyzer as blood pump and single-lumen access. ASAIO J 46:223, 2000.

Ash SR, Carr DJ, Harker K, Truitt RB, Korkor A. Every-other night hemodialysis with single-lumen access, plate dialyzer as blood pump, and sorbent column (SHD). Int J Artif Organs 32:575, 2000.

Sorbent Suspension Dialysis System; the Biologic-DTÒ System, HemoTherapies Liver Dialysis Unit Ô

Liver Failure – Journal Articles

Ash SR. Treatment of acute hepatic failure with encephalopathy: a review. Int J Artif Organs 14(4):191-195, 1991.

Ash SR, Blake DE, Carr DJ, Carter C, Howard T, Makowka L. Neurologic improvement of patients with hepatic failure and coma during sorbent suspension dialysis. ASAIO Trans 37(3):M332-M334, 1991.

Ash SR, Blake DE, Carr DJ, Carter C, Howard T and Makowka L. Clinical effects of a sorbent suspension dialysis system in treatment of hepatic coma (the BioLogic-DT). Int J Artif Organs 15(3):151-161, 1992.

Ash SR, Carr DJ, Blake DE, Rainier JB, Demetriou AA, Rozga J. Effect of sorbent-based dialytic therapy with the Biologic-DT on an experimental model of hepatic failure. ASAIO J 39(3):M675-M680, 1993.

Ash SR, Hemodiabsorption in treatment of acute hepatic failure and chronic cirrhosis with ascites. Artif Organs 18(5):355-362,1994.

Ash SR, Hemodiabsorption in the treatment of acute hepatic failure. ASAIO J 40(1):80-82, 1994.

Wilkinson AH, Ash SR, Nissenson AR. Hemodiabsorption in treatment of hepatic failure. Journal of Transplant Coordination 8:43-50, 1998.

Ash SR. Letter to the Editor. Artif Organs 22(6):518-519, 1998.

Ash SR. Overview of the treatment of fulminant hepatic failure. 2000 UpToDate, Burton Rose Editor.

Liver Failure - Abstracts

Ash SR, Wilkinson AH, Hughes RD, Williams R. BioLogic-DT System in treatment of acute hepatic coma; results of randomized prospective controlled trials. American Society for Artif Organs. 42(2)11, March-April 1996.

Ash SR, Patzer JF, Carr DJ, Blake DE. Push-pull sorbent-based pheresis in treatment of acute hepatic failure with coma (AHF). Amer. Soc. for Artificial Internal Organs. 43(2):18, March-April 1997.

Ash S, Wilkinson A, Hughes R, Williams R. BioLogic-DT system in treatment of acute hepatic coma; results of randomized, prospectively controlled trials. J Hepatology 25(1):101, 1996.

Mazariegos GV, Ash SR, Patzer JF. Preliminary results: randomized clinical trial of the BioLogic-DT in treatment of acute hepatic failure (AHF) with coma. Artif Organs 21(6):529, 1997.

Mazariegos GV, Kramer DK, Linden P, Pinna A, Fung JJ, Ash SR, Patzer JF. Treatment of hepatic failure with advanced encephalopathy using the BioLogic-DT: Preliminary clinical results. Critical Care Society, 1998.

Ash SR, Leamon KD, Gingrich CH. Hemodiabsoption (The BioLogic-DT System) in treatment of hepatic failure with encephalopathy: Summary of randomized, prospectively controlled clinical trials. Hepatology 28(4, Pt. 2):497A, 1998.

Ash SR, Kuczek T, Foster DE, Blake DE, Gingrich CH. Hemodiabsorption in treatment of hepatic failure: summary of randomized, prospectively controlled clinical trials with the BioLogic-DT System. ASAIO J 45:202, 1999. (Slide Presentation ASAIO `99.)

Ash SR, Kuczek T, Foster DE, Blake DE, Gingrich CH, Mankus RA. Hemodiabsorption in treatment of hepatic and hepatorenal failure: summary of randomized, prospectively controlled clinical trial. J Am Soc Nephrol 10:628A, 1999.

Ash SR, Kuczek T, Foster DE, Blake DE, Gingrich CH. Hemodiabsorption in treatment of hepato-renal failure: Summary of randomized, prospectively controlled clinical trials. Hepatology 30:169A, 1999.

Ash SR, Kuczek T, Foster DE, Blake DE, Gingrich CH. Liver dialysis in treatment of hepatic failure and hepatorenal failure: Summary of randomized, prospectively controlled clinical trials. Blood Purif 18:67, 2000.

Ash SR, Kuczek T, Blake DE, Gingrich CH. Liver dialysis in treatment of hepatorenal failure: randomized clinical trials and clinical experience. ASAIO J 46:223, 2000.

Ash S, Kuczek T, Foster D, Steczko J, Blake D, Gingrich C. Liver dialysis in treatment of hepatic failure and hepatorenal failure: randomized clinical trials and recent improvements. Int J Artif Organs 23:534, 2000.

Ash SR, Kuczek T, Steczko J, Blake DE, Gingrich CH. Randomized clinical trials of liver dialysis in treatment of hepatic failure and hepatorenal failure. J Am Soc Nephrol 11:173A, 2000.

Drug Overdose – Journal Articles

Shihab-Eldeen AA, Peck GE, Ash SR, Kaufman GM. Evaluation of the sorbent suspension reciprocating dialyser in the treatment of overdose of paracetamol and phenobarbitone. J Pharm Pharmacol 40:381-387, 1988.

Ash SR, Blake DE, Carr DJ. Increasing selectivity of chemical removal from blood by pre-loading charcoal of the BioLogic-DT. American Filtration Society 7:329-332, 1993

Ash SR, Blake DE, Carr DJ, Rainier JB, Gingrich CH, Truitt RB. Selective chemical removal from blood by a sorbent suspension dialysis system (Biologic-DT). American Filtration Society 7:325-328, 1993.

Ash SR, Levy H, Akmal M, Mankus RA, Sutton JM, Emery DR, Scanlon JC, Blake DE, Carr DJ. Treatment of severe tricyclic antidepressant overdose with extracorporeal sorbent detoxification. Advances in Renal Replacement Therapy 9:31-41, 2002.

Ash SR, Caldwell CA, Singer GG, Lowell JA, Howard TK, Rustgi VK. Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure with extracorporeal sorbent-based devices. Advances in Renal Replacement Therapy 9:42-53, 2002.

Drug Overdose - Abstracts

Ash SR, Rustgi VK. Recovery of hepatic function following treatment of acetaminophen overdose with the BioLogic-DT. Abstract #348, pg. A-88. Proceeding from Digestive Disease Week. May 1997.

Lowell JA, Caldwell CA, Singer G, Rustgi VK, Ash SR, Wendon JA, Williams R. Treatment of acetaminophen-induced hepatotoxicity and fulminant hepatic failure by the BioLogic-DT® System. Hepatology 26:4(2):252A, 1997.

Ash SR, Caldwell CA, Singer GG, Lowell JA, Howard TK, Rustgi VK, Hughes R, Ellis T, Wendon JA, Williams R. Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure by the BioLogic-DT system. ASAIO J 45:204, 1999. (Poster presentation at ASAIO `99.)

Mankus RA, Ash SR, Levy H, Akmal M, Blake DE, Carr DJ, Emery DR, Scanlon JC. Treatment of severe tricyclic antidepressant (TCA) overdose using hemodiabsorption by the BioLogic-DT system. ASAIO J 45:123, 1999. (Poster presentation at ASAIO `99.)

Ash SR, Levy H, Akmal M, Mankus RA, Sutton JM, Emery DR, Scanlon JC, Blake DE, Carr DJ. Treatment of severe tricyclic antidepressant overdose with the BioLogic-DT System. J Am Soc Nephrol 10:628A, 1999.

Ash SR, Caldwell CA, Singer GG, Lowell JA, Howard TK, Rustgi VK. Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure by the BioLogic-DT System. Hepatology 30:552A, 1999.

Sorbent Based Pheresis; the BioLogic-DTPF System Ô

Liver Failure – Journal Articles

Ash SR, Blake DE, Carr DJ, Harker KD. Push-pull sorbent-based pheresis for treatment of acute hepatic failure: The BioLogic-detoxifier/plasma filter System. ASAIO J 44(3):129-139, 1998.

Ash SR, Knab WR, Blake DE, Carr DJ, Steczko J, Harker KD, Levy H. Push-pull sorbent-based pheresis and hemodiabsorption in treatment of hepatic failure: preliminary results of a clinical trial with the BioLogic-DTPF System. Therapeutic Apheresis 4:218-228, 2000.

Steczko J, Bax KC, Ash SR. Effect of hemodiabsorption and sorbent-based pheresis on amino acid levels in hepatic failure. Int J Artificial Organs 23:375-388,2000.

Ash SR. Powdered Sorbent liver dialysis and pheresis in treatment of hepatic failure. Therapeutic Apheresis 5(5):404-416, 2001.

Ash SR. Extracorporeal blood detoxification by sorbents in treatment of hepatic encephalopathy. Advances in Renal Replacement Therapy 9:3-18, 2002.

Liver Failure - Abstracts

Ash SR, Carr DJ, Blake DE, Harker KD. Push-pull sorbent-suspension pheresis for treatment of acute hepatic failure: the BioLogic-DTPF. ASAIO J 42(2):11, 1996.

Ash SR, Knab WR, Steczko J, Carr DJ, Blake DE. Hepatic failure treatment by powdered sorbent pheresis - the BioLogic-DTPF System. ASAIO J 44(2):92A, 1998.

Ash SR, Knab WR, Blake DE, Carr DJ, Harker DK, Levy H. The BioLogic-DTPF System in treatment of fulminant hepatic failure: preliminary results of a clinical trial. Hepatology 28(4, Pt. 2):496A, 1998.

Ash SR, Blake DE, Carr DJ, Harker KD, Levy H. Push-pull sorbent-based pheresis (BioLogic-DTPF) in treatment of hepatic failure: preliminary results of a clinical trial. ASAIO J 45:203, 1999. (Poster presentation at ASAIO `99).

Steczko J, Ash SR, Bax KC, Blake DE. Amino acid profiles during hepatic failure during sorbent-based dialysis and sorbent-based pheresis treatment. Presented at 10th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism, Turkey, 1999.

Ash SR, Blake DE, Carr DJ, Harker KD, Levy H. Push-pull sorbent-based pheresis (BioLogic-DTPF System) in treatment of hepatic failure: preliminary results of a clinical trial. Presented at for 10th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism, Turkey, 1999.

Ash SR, Blake DE, Carr DJ, Harker KD, Levy H. Push-pull sorbent-based pheresis (BioLogic-DTPF System) in treatment of hepatic failure: preliminary results of a clinical trial. Therapeutic Apheresis 3(2):113, 1999.

Ash SR, Bax KC, Steczko J. Changes in plasma amino acid levels in hepatic failure patients during sorbent-based dialysis and sorbent-based pheresis treatment. Hepatology 30:675A, 1999.

Ash SR, Carr DJ. Characterizing Activated Carbon for Sorbent Therapy. ASAIO J, 2006.

Sepsis – Journal Articles

Levy H, Ash SR, Knab WR, Steczko J, Carr DJ, Blake DE. Systemic inflammatory response syndrome (SIRS) treatment by powdered sorbent pheresis: the BioLogic-Detoxification Plasma Filtration System. ASAIO J 44(5):M659-M665, 1998.

Steczko J, Ash SR, Blake DE, Carr DJ, Bosley RH. Cytokines and endotoxin removal by sorbents and its application in push-pull sorbent-based pheresis: The BioLogic-DTPF System. Artif Organs 23:310-318, 1999.

Ash SR, Steczko J, Levy H, Blake DE, Carr DJ. Treatment of systemic inflammatory response syndrome by push-pull powdered sorbent pheresis: A Phase 1 clinical trial. Therapeutic Apheresis 5 (6):497-505, 2001

Peter AT, Ash SR, Steczko J, Turek JJ, Blake DE, Carr DJ, Knab WR, Bosley RH. Push-pull sorbent-based pheresis treatment in an experimental canine endotoxemia model: preliminary report. Intern J Artif Organs 22:177-188, 1999.

Sepsis - Abstracts

Steczko J, Ash SR, Carr DJ, Blake DE. Cytokine removal from plasma by push-pull sorbent-based pheresis (the BioLogic-DTPF System). ASAIO J 43(2):82, 1997.

Ash SR, Steczko J, Carr DJ, Blake DE. Cytokine, endotoxin, and bilirubin removal from plasma by push-pull sorbent-based pheresis (the BioLogic DTPF System). Artif Organs 21(6):499, 1997.

Ash SR, Steczko J, Carr DJ, Blake DE. Cytokine and bilirubin removal in acute hepatic failure by push-pull sorbent-based pheresis (the BioLogic-DTPF System). Hepatology 26(4p2):475A, 1997.

Steczko J, Ash SR, Levy H, Carr DJ, Blake DE. Cytokine removal from plasma of patients with sepsis by the BioLogic-DTPF System. Hepatology 26:4(2):604A, 1997.

Levy H, Ash SR, Knab WR, Steczko J, Carr DJ, Blake DE. Systemic inflammatory response syndrome (SIRS) treatment by powdered sorbent pheresis: the BioLogic-DTPF System. ASAIO J 44(2):81A, 1998.

Levy H, Ash SR, Steczko J, Carr DJ. Cytokine removal from plasma of patients with SIRS by the BioLogic-DTPF. Poster presentation at 18th International Symposium. Critical Care 2(1), March 1998.

Ash SR, Levy H, Mankus RA, Knab WR, Steczko J, Carr DJ, Blake DE. Treatment of systemic inflammatory response syndrome (SIRS) by powdered sorbent pheresis: the BioLogic-DTPF System. J Am Soc Nephrol 9:471A, 1998.

Levy H, Ash SR, Knab WR, Steczko J, Carr DJ, Blake DE. Treatment of systemic inflammatory response syndrome (SIRS) by powdered sorbent pheresis: the BioLogic-DTPF System. Hepatology 28(4, Pt.2):225A, 1998.

Ash SR, Levy H, Steczko J, Carr DJ, Blake DE. Push-pull sorbent-based pheresis (BioLogic-DTPF System) in treatment of systemic inflammatory response syndrome (SIRS). Therapeutic Apheresis 3(1):113, 1999.

Whole Body Hyperthermia; BioLogic-HT System, ThermoChem System

Hyperthermia – Journal Articles

Steinhart CR, Ash SR, Gingrich C, Sapir D, Keeling GN, Yatvin MB. Effect of whole body hyperthermia on AIDS patients with Kaposi’s sarcoma: a pilot study. J Acquired Deficiency Syndromes and Human Retrovirology 11(3):271-281, 1996.

Ash SR, Steinhart CR, Curfman MF, et al. Extracorporeal whole body hyperthermia treatments for HIV infection and AIDS. ASAIO J 43(5):M830-M838, 1997.

Hyperthermia Abstracts

Ash SR, Steinhart CR, Curfman MF, Gingrich CH, Sapir DA, Yatvin MB. Whole body hyperthermia treatments for AIDS; a randomized, controlled trial. American Society for Artif Organs 42(2):98, 1996.

Yatvin MB, Shenoy M, Li W, Steinhart C, Ash SR, Gingrich C, Sapir D, Keeling, G. Whole-body hyperthermia to treat HIV-infection. 5th Annual AIDS Day Conference, Munich, Germany, January 1996.

Ash SR, Steinhart CR, Curfman MF, Gingrich CH, Sapir DA, Yatvin MB. Whole body hyperthermia treatments for AIDS; combination with protease inhibitor therapy. Amer. Soc. for Artificial Internal Organs. 43(2):34, 1997.

Ash S, Steinhart C, Curfman M, Gingrich C, Sapir D, Yatvin M. Whole body hyperthermia treatment (WBHT) for AIDS: a randomized, controlled study in patients with drug treatment failure. Artif Organs 21(6):567, 1997.

Peritoneal Dialysis and Access:  T-Fluted Catheter, Ash Advantage

PD - Articles

Ash SR and Manfredi F. Directed biopsy using a small endoscope: thoracoscopy and peritoneoscopy simplified. New Eng J Med 291(26):1398-1399, 1974.

Thornhill JA, Ash SR, Dhein CR, Polzin DJ and Osborne CS. Peritoneal dialysis with the Purdue Column Disc Catheter. The Minnesota Veterinarian 20(2):27-33, 1980.

Ash SR, Johnson H, Hartman J, Granger J, Koszuta J, Sell L, Dhein C, Blevins W, and Thornhill JA. The column disc peritoneal catheter: a peritoneal access device with improved drainage. ASAIO J. 2:109-115, 1980.

Thornhill JA, Dhein CR, Johnson H and Ash SR. Drainage characteristics of the column disc catheter: a new chronic peritoneal access catheter. Proc. Clin Dial Transplant Forum 10:119-125, 1980.

Dhein CR, Thornhill JA, Chiosi C, Ash SR. Protein and bacterial rejecting filters for peritoneal dialysis. Kidney Int 19(1):145, 1981.

Ash SR, Wolf GC and Block R. Placement of the Tenckhoff peritoneal dialysis catheter under peritoneoscopic visualization. Dialysis & Transplantation 10(5):383-386, 1981.

Ash SR. Outflow volume measurements during CAPD: a simplified method. Contemporary Dialysis 2(1):38, 1981.

Ash SR, Wimberly AL and Mertz SL. Peritoneal dialysis for acute and chronic renal failure: an update. Hosp Practice 18(1):179-210, 1983.

Ash SR, Handt A and Block R. Peritoneoscopic placement of the Tenckhoff catheter - further clinical experience. PD Bulletin 3(1):8-12, 1983.

Ash SR, Streuwing JD. Clinical trials of the column disc peritoneal catheter (Lifecath™). PD Bulletin 3(2):77-80, 1983.

Ash SR, Horswell R, Heeter EM, Block R. Effect of the PeridexÒ Filter on peritonitis rates in a CAPD population. PD Bulletin 3(2):89-93, 1983.

Winchester JF, Ash SR, Bousquet G, Rakowski TA, Barnard WF, Heeter E, and Haley S. Successful peritonitis (P) reduction with a unidirectional bacteriologic CAPD filter (F). Proc. of 3rd National CAPD Conference, Kansas City, Feb. 13-16, 1983.

Ash SR, Winchester JF. Effect of the PeridexÒ filter on peritonitis rates in a CAPD population. Proc. of 3rd National CAPD Conference, Kansas City, Feb. 14-16, 1983.

Ash SR, Carr DJ. Hydraulic resistance and biocompatibility of the Tenckhoff and Lifecath™ peritoneal catheters. Proc. of 3rd National CAPD Conference, Kansas City, Feb. 14-16, 1983.

Handt AE, Ash SR. A spike exchange technique for the patient with visual or strength impairment. Proc. of 3rd National CAPD Conference, Kansas City, Feb. 14-16, 1983.

Ash SR, Slingeneyer A and Schardin K. Peritoneal access using the column disc catheter. Perspectives in Peritoneal Dialysis 1(2):9-11, 1983.

Winchester JF, Ash SR, Bousquet G, Rakowski TA, Barnard WF, Heeter E and Haley S. Successful peritonitis reduction with a unidirectional bacteriologic CAPD filter. Trans Am Soc Artif Inter Organs 29:611-616, 1983.

Thornhill JA, Hartman J, Boon GD, Riviere JE, Jacobs D, Ash SR. Support of an anephric dog for 54 days with ambulatory peritoneal dialysis and a newly designed peritoneal catheter. Am J Vet Res 45(6):1156-1161, 1984.

Ash SR. Peritoneal access devices: a search for biocompatibility. Int J Artif Org 7(3):115-118, 1984.

Ash SR. Effect of peritoneal access devices on the incidence of peritonitis. Trans Am Soc Artif Inter Organs 30:686-690, 1984.

Handt AE, Ash SR. Longevity of Tenckhoff catheters placed by the VITEC™ peritoneoscopic technique. Perspectives in Peritoneal Dialysis. 30-32, 1984.

Ash SR. Biocompatibility and hydraulic function of Tenckhoff and LifeCath™ catheters. Peritoneal Dialysis Bulletin - Supplement. S103-S106, 1984.

Ash SR, Winchester JF. New devices, solution composition and alternatives. Peritoneal Dialysis Bulletin - Supplement. S118 - S120, 1984.

Suki WN, Ash SR, et al. Multicenter evaluation of a bagless CAPD system. ASAIO Trans 32(1):572-574, 1986.

Ash SR. Chronic peritoneal dialysis catheters: effects of catheter design, materials and location. Seminars in Dialysis 3(1):39-46, 1990.

Ash SR, Janle EM, Hucker EM. A comparison of peritoneal dialysance (D) during CAPD, intermittent peritoneal dialysis (IPD) and tidal PD (TPD) in awake normal dogs. Adv Perit Dial 7:21-25, 1991.

Ash SR. A break-in period is unnecessary. Seminars in Dialysis 5(3):199-201, 1992.

Gokal R, Ash SR, et al. Peritoneal catheters and exit-site practices: toward optimum peritoneal access. Perit Dial Int 13(1):29-39, 1993.

Ash SR. Who should place peritoneal catheters? A nephrologist's view. Nephrol News Issues 7(5):33-34, 1993.

Contreras MR, Ash SR, et al. Peritonitis due to Moraxella (Branhamella) catarrhalis in a diabetic patient receiving peritoneal dialysis. South Med J 86(5):589-590, 1993.

Ash SR, Janle EM. T-fluted peritoneal dialysis catheter. Adv Perit Dial, 9(1):223-226, 1993.

Gokal R, Ash SR, et al. Peritoneal catheters and exit-site practices: toward optimum peritoneal access. Peritoneal Dialysis Int 13:29-39, 1993.

Ash SR, Mertz SL. Peritoneal dialysis for acute renal failure: the safe, effective, and low-cost modality. Advances in Ren Replace Ther 2(2):160-163, 1995.

Contreras MR, Ash SR, Swick SD, Grutzner J. Peritonitis due to Moraxellla (Branhamella) catarrhalis in a diabetic patient receiving peritoneal dialysis. Southern Medical Journal 86:589-590, 1993.

Ash SR, Bever SL. Peritoneal dialysis for acute renal failure: the safe, effective, and low-cost modality. Adv Ren Replace Ther 2(2):160-163, 1995.

Ash SR. Peritoneal access devices for intraperitoneal chemotherapy. Review. Cancer Treat Res. 82:387-413, 1996.

Ash SR, Janle EM. Continuous flow-through peritoneal dialysis (CFPD): comparison of efficiency to IPD, TPD, and CAPD in an animal model. Amer. Soc. For Artificial Internal Organs 43(2):80. 1997.

Ash SR. Obtaining adequate visualization during peritoneoscopic placement of peritoneal catheters. Peritoneoscopy Today. 1(1), 1997.

Ash SR, Janle EM. Continuous flow-through peritoneal dialysis (CFPD): comparison of efficiency to IPD, TPD, and CAPD in an animal model. Peritoneal Dialysis Int 17(4):365-372, 1997.

Ash SR. Bedside peritoneoscopic peritoneal catheter placement of Tenckhoff and newer peritoneal catheters. Advances in Peritoneal Dialysis 14:75-79, 1998.

Roberts M, Ash SR, Lee DBN. Innovative techniques for increasing peritoneal dialysis efficiency: flow-thru and regeneration. ASAIO J 45(5) 372-378, 1999.

Gokal R, Alexander S, Ash S, et al. Peritoneal catheters and exit-site practices: toward optimum peritoneal access: 1998 update. Perit Dial Int 18:11-33, 1998.

Ash SR, Bever SL. Burying peritoneal catheters. Peritoneoscopy Today 1(2):3-5, Spring 1998.

Ash SR. Peritoneal catheter designs and placement methods; they do make a difference.  Contemporary Dialysis & Nephrology February 2000, pp. 24-29.

Ash SR. Peritoneal dialysis in acute renal failure of adults: the safe, effective and low-cost modality. Contrib to Nephrology, Vol. 132, pp. 210-221, 2001.

Ash SR. Ash AdvantageÔ catheter. Perit Dial Today 7(1):15, 2001.

Ash SR, Sutton JM, Mankus RA, Rossman J, de Ridder V, Nassvi MS, Ross J. Clinical trials of the T-Fluted (Ash Advantage) peritoneal dialysis catheter. Advances in Renal Replacement Therapy, V 9, No 2 (April), 2002: pp 133-143 -

Ash SR. Chronic peritoneal dialysis catheters: procedures for placement, maintenance, and removal. Seminars in Nephrology  V 22, No 3 (May): pp 221-236

Ash SR. Chronic Peritoneal Dialysis Catheters: Overview of design, placement, and removal procedures. Seminars in Dialysis. V 16, No 4 (July) 2003:pp. 323-334.

Ash SR. Chronic peritoneal dialysis catheters: Challenges and design solutions. Int J Artif Organs 2006; 29:85-94

PD - Abstracts

Ash SR, Janle E. Continuous flow-through peritoneal dialysis (CFPD): comparison of efficiency to IPD, TPD, and CAPD in an animal model. Abstract #337. Artif Organs 21(6):564, 1997.

Ash SR, Sutton JM, Mankus RA. Clinical trials of the T-Fluted (Ash AdvantageÔ) peritoneal dialysis catheter. J Am Soc Nephrol 9:190A, 1998.

Ash SR, Sutton JM, Mankus RA. The AdvantageÔ (T-Fluted) peritoneal dialysis catheter. PDI 19, Suppl 1: S39, 1999.

Ash SR, Sutton JM, Makus RA, Rossman J, deRidder V, Nassvi MS, Ross J. Clinical trials of the Ash Advantage peritoneal dialysis catheter. PDI 20:S46, 2000.

Mankus RA, Ash SR, Sutton JM, Schweikert T. The Duo Split acute hemodialysis catheter: a two-limbed acute hemodialysis catheter with novel technique for insertion. ASAIO J 46:222, 2000.

Hemodialysis

Dialysis - Articles

Ash SR, Thornhill JA, Dhein CR and Rebar AH. Dialytic Support of dogs with clinically occurring renal failure: a realistic model of acute renal failure in man. Clin Exp Dial Aphersis 6(1):25-44, 1982.

Ash SR and Millikan M. Optimizing tobramycin therapy in a hemodialysis patient. Int J Artif Organs 5(4):279-280, 1982.

Lowrey SJ and Ash SR. Direct blood pressure recording during acute hemodialysis: a simplified method. Nephrol Nurse 4(4):28-32, 1982.

Ash SR. The resurrection of home hemodialysis. Contemporary Dialysis & Nephrology 8(9):34-35, 1987.

Ash SR. Editorial. An explanation for uremic hypothermia. Int J Artif Organs 14(2):67-69, 1991.

Ash SR, Gloeckner PJ, Barnett SL. Lack of removal of calcitriol during hemodialysis procedures. J Am Soc Nephrol 8(10):1587-1591, 1997.

Dialysis - Abstracts:

Stakisaitis D, Ash SR, Daugirdas JT. Use of optical hematocrit or cardiac index to predict hypotension in hypotensive-prone dialysis patients. Abstract #1021. JASN 6(3):614, 1995.

Bern DS, Sherman JD, Ash SA, Marte JC, Willis RR, Braun R, Muldoon BS. Ammonium removal with a novel zirconium silicate. ASAIO J 47:151, 2001.

Venous Access; IV Therapy; IFADÔ, IVADÔ Ò, Ash Split CathÒ, Citrate Lock

Tsuchida RK, Hillberry BM, Ash SR, Belcastro PF. A computerized IV fluid delivery system with automatic rate adjustment. Amer. J. Intravenous Therapy & Clinical Nutrition 10(7):19-26, 1983.

Kaufman GM and Ash SR. Intravenous transcutaneous vascular access device. Trans Am Soc Artif Intern Organs 30:458-462, 1984.

Ash SR and Carr DJ. Fluid dynamics, basic concepts, and computer interfaced electronic rate control instruments: advantages and applications. In: Turco S, ed. The Sourcebook for IV Therapy. IVAC Corporation, 1985.

Ash SR. The perils of IV potassium: are they overrated? In: Turco S, ed. Parenterals. 1986.

Ash SR and Carr DJ. Understanding fluid dynamics when choosing I.V. control systems. In: Turco S, ed. Parenterals. Feb/March 1987.

Roberts RK, Hillberry BM, Thornhill JA, Blevins WE and Ash Sr. The difficulties of drawing blood from venous catheters: a hydraulic model. J Parenter Sci Technol 41(1):3-8, 1987.

Ash SR, Fritton CW, Carr DJ. Clinical trials of the indwelling fistula access device (IFAD). ASAIO Abst, 16:73, 1987.

Lowrey SJ, Ash SR, et al. Diminishing the risks of I.V. potassium chloride. Nursing 18(6):64, 1988.

Mankus RA, Ash SR, Sutton JM. Comparison of blood flow rates and hydraulic resistance between the Mahurkar Catheter, the Tesio Twin Catheter, and the Ash Split Cath. ASAIO J 44(5):M532-534, 1998.

Mankus RA, Ash SR, Sutton JM. Ash Split-CathÔ dual-lumen central venous catheter: flow rate comparison with TesioÒ and MahurkarÒ catheters. Abstract. ASAIO J 44(2):64A, 1998.

Mankus RA, Ash SR, Sutton JM. Comparison of blood flow rates (Qb), hydraulic resistance ® and longevity between the Ash Split CathÔ hemodialysis catheter and MahurkarÒ and TesioÒ Twin catheters. J Am Soc Nephrol 9:177A, 1998.

Ash SR, Mankus RA, Sutton JM, Criswell ER, Crull RC, White LE, Lowrey SJ. Concentrated citrate/gentamicin for catheter lock solution. ASAIO J 45:180, 1999.

Mankus RA, Ash SR, Sutton JM. Survival and hydraulic function of the Ash Split Cath hemodialysis catheter. J Am Soc Nephrol 10:211A, 1999.

Ash SR, Mankus RA, Sutton JM, Criswell ER, Crull RC, White LE, Lowrey SJ. Concentrated sodium citrate as catheter lock solution. J Am Soc Nephrol 10:272A, 1999.

Ash SR, Mankus RA, Sutton JM. Survival and hydraulic function of the Ash Split Cath hemodialysis catheter. ASAIO J 46:223, 2000.

Ash SR, Mankus RA, Sutton JM, Smelzer B, Ing T. Concentrated citrate (23%) for catheter lock solution. ASAIO J 46:222, 2000.

Ash SR, Mankus RA, Sutton JM, Criswell RE, Crull CC, Velasquez KA, Smeltzer BD, Ing TS. Concentrated sodium citrate (23%) for catheter lock. Hemodialysis International 4:22-31, 2000.

Ash SR, Mankus RA, Sutton JM. 83% one-year survival of tunneled IJ catheters using the Ash Split Cath. J Am Soc Nephrol 11:179A, 2000.

Ash SR. The evolution and function of central venous catheters for dialysis. Seminars in Dialysis 14:416-424, 2002.  (Note: ASDIN issue)

Ash SR, Mankus RA, Sutton JM, Spray M. The Ash Split Cath as long-term IJ access: hydraulic performance and longevity. J Vascular Access 3:3-9, 2002.

Ash SR. Chronic Central Venous Catheters for Dialysis and the Ash Split Cath Catheter: Rationale and Clinical Experience. ContribNephrol. 2004;142:128-52 Review.

Peter AT, Steczko J, Ash SR.  Catheter-related bacteremia in rats: A Preliminary report on the effect of methylene blue coated catheter, Indian Journal of Experimental Biology, vol. 44, March 2006, pp183-188.

Venous Access; IV Therapy; IFADÔ, IVADÔÒ, Ash Split CathÒ, Citrate Lock Abstracts

Ash Sr, Steczko, J, Brewer BS, Winger RK. Microbial Inactivation Properties of Methylene Blue-Citrate Solution.  ASAIO J 2006

Clinical Information Computer Systems; SmartChart

Ash SR, Mertz SL, and Ulrich DK.

Streamlining of problem-oriented notation with a microcomputer. Presented at the AAMSI, October 1982.

Mertz SL, Ash SR, and Farrell J. The CNS in the ICU: a bedside notation for nurses. Proc. of SCAMC, p. 577-582, 1982.

Ash SR. Mertz SL, and Ulrich DK. The computerized notation system: a portable, self-contained system for entry of physicians' and nurses' notes. Proc SCAMC, p. 129-135, 1981, and J of Clinical Engineering, 8:2:147-155, April/June 1983.

Ash SR. A briefcase computer for patient record in the clinic and hospital. Consultant, 23:5, May 1983.

Ash SR, Mertz SL, Ulrich DK. The computerized notation system (CNS): a microcomputer system for rapid entry of notes by physicians and nurses. J Med Syst 7(3):193-203, 1983.

Ash SR and Ulrich DK. Direct entry of patient data to a portable briefcase computer: interface with overview medical database at the office. Proc of SCAMC  350-352, 1983.

Ash SR. What are the limiting factors in practitioners uses of computers: the key research question. Med Inf (Lond) 9(3-4):268-269, 1984.

Ash SR and Ulrich DK. The pocket medical record - Do we need a centralized medical database? J of Clinical Engineering 8(4):307-314, 1983.

Ash SR and Ulrich DK. CNS: A problem-oriented notation system for briefcase computers. Physicians and Computers 1(8):32-40, 1983.

Ash SR and Ulrich DK. A direct data entry system for physicians and nurses. Proc of SCAMC p. 98, 1983.

Ash SR. The physician-computer interface: the major limitation of a digital clinical database. Healthcare Computing & Communication 1(2):42-47, 1984.

Ash SR. Using a portable computer for patient records. Physicians Financial News, p. C-7, February 1984.

Ash SR. Data can be rapidly fed into computer right at bedside. Cardiology Times 3:4:29, April 1984.

Ash SR, Handt AE, Ulrich DK, Hrabel D and Wimberly AL. Total Recall™ and Total Control™ in the specialty care unit: a database for the science, practice, and business of medicine Proc of SCAMC p. 796-799, 1984.

Ash SR, Ulrich DK and Laxton DE. The Total RecallÔ program: a relational office database interface with briefcase computers. Proc of SCAMC, p. 429-432, 1984.

Ash SR. A review of automated clinical records in nephrology. Can clinical records problems be solved? Contemporary Dialysis & Nephrology, Parts I through V, January-April and November 1986.

Ash SR. Automated clinical record systems: the ideal and the reality. In: Cushing M, ed. Physicians Guide to Computers. Deerfield Beach, FL: VCH Publishers, 1986.

Ash SR and Ulrich DK. Portable and desktop microcomputers for patient care charting. J Med Syst 10(4):361-373, 1986.

Ash SR and Ulrich DK. The SmartChart program: a patient information system for better chart maintenance. Resident & Staff Physician 33(1):132-142, 1987.

Ash SR, Barnett ME, Sutton JM, Lowrey S and Ulrich DK. Evolution of the medical record format during two years’ use of an open-format microcomputer charting system. J Clin Eng 16(4):337-348, 1991.

Gray DL, Ash SR, Jacobi J, Michel AN. The training and use of an artificial neural network to monitor use of medical in treatment of complex patients. J Clin Eng 16(4):331-336, 1991.

Ash SR. Computer-based charting (Part I). Physicians & Computers 14(7):24-35, 1997.

Ash SR. Computer-based charting (Part II). Physicians & Computers 14(8):16-35, 1997.

Chemical Monitoring and Diabetes; Capillary Filtrate CollectorÔ

Newhouse VL, Hoover ML , Ash SR. The detection of blood impurities using ultrasound Doppler. Ultrason Imaging 2(4):370-380, 1980.

Janle-Swain E, Thornhill JA, Carter JM, Hinsmann E, Jackson HD, Ash SR. Case study of a diabetic dog with chronic membranous glomerulopathy treated with continuous intraperitoneal insulin infusion. Am J Vet Res 43(11):2044-2049, 1982.

Janle-Swain E, Thornhill JA, Carter JM, Hinsman E, Jackson HD, Swain S, Ash SR. Improvement in kidney function with continuous intraperitoneal insulin infusion in a diabetic dog with chronic membranous glomerulopathy. Diabetic Nephropathy 2:16-22, 1983.

Janle-Swain E, Turek J, Van Vleet J, and Ash SR. Use of a capillary filtrate collector for monitoring glucose levels in diabetics. ASAIO Trans 33(3):336-340, 1987.

Janle-Swain E, Clark T, Ash SR. Use of an ultrafiltrate sampling probe to control glucose levels in a diabetic cat. Case Study (Bioanalytical Systems, Inc.) March 1992.

Ash SR, Poulos JT, Rainier JB, Zopp WE, Janle-Swain E, Kissinger PT. Subcutaneous capillary filtrate collector for measurement of blood glucose. ASAIO J 38(3):M416-M420, 1992.

Ash SR, Rainier JB, Zopp WE, Truitt RB, Janle EM, Kissinger PT, Poulos JT. Subcutaneous capillary filtrate collector (CFC) for measurement of blood chemistries. ASAIO J 39(3):M699-M705, 1993.

Ash SR, Zopp WE, Truitt RB, Janle EM, Kissinger PT. Subcutaneous ultrafiltration fibers for chemical sampling of blood: the capillary filtrate collector (CFC). American Society of Filtration 7:316-319, 1993.

Ash SR, Peyton JD, Rainier JB. Blood glucose measurement by capillary filtrate collector (CFC) and glucose oxidase sensor. American Chemical Society 1993.

Janle EM, Ash SR, Zopp WE, Kissinger PT. Determination of glucose in microliter samples of in vivo ultrafiltrates and microdialysates using amperometric flow injection analysis with an enzyme reactor. Current Separations 12(1):14-17, 1993.

Janle EM, Ash SR. Comparison of urea nitrogen and creatinine concentrations in dog plasma and subcutaneous ultrafiltrate samples. Current Separations 12(4):169-171, 1994.

Ash SR, Badylak SF, Jones J, Byrd A. Sub-Q ultrafilter/infusion device (SQUID) for continuous glucose measurement and feedback-controlled insulin infusion. ASAIO J 45:198, 1999.

Ash SR, Badylak S, Jones J, Byrd A. Capillary Filtrate Collector (CFC) and Subcutaneous Ultrafilter/Infusion Device (SQUID) for continuous glucose measurement and feedback-controlled insulin infusion. The Electrochemical Society, Meeting Abstracts 2000-I, Abstract No. 1250, 2000.

Gea Leegsma-Vogt, Elsa Janle, Stephen R. Ash, Kor Venema, Jakob Korf. Utilization of in vivo ultrafiltration in biomedical research and clinical applications. Life Sci. 2003 Sep 5;73(16):2005-18.

Nephrology/General

Ash SR, Cuppage FE. Shift toward anaerobic glycolysis in the regenerating rat kidney. Am J Pathol 60(3):385-402, 1970.

Ash SR. Letter: Measurement of thickness of pleural effusions using an impedance probe: an aid in thoracentesis. Ann Intern Med 82(3):380-381,1975.

Ash SR, Cuppage FE, Hodes ME, Selkurt EE. Culture of isolated renal tubules: a method of assessing viability of normal and damaged cells. Kidney Int 7(1):55-60, 1975.

Takayasu M, Duske N, Ash SR, Freidlander FJ. HGMS studies of blood cell behavior in plasma. IEEE Trans on Magnetics 18(6):1520-1522, 1982.

Ash SR, Jacobi J. A nomogram for drug dosage in renal failure based on mean plasma concentrations. Int J Artif Organs 6(3):101-104, 1983.

Ash SR, Bungu Z, Regnier F. Anion exchange chromatography and double-diffusion cells in the study of middle molecules. Kidney Int 24(2):250-255, 1983.

Larson EA…Ash SR, et al. Phosphate binding gels: balancing phosphate adsorption and aluminum toxicity. Kidney Int 29(6):1131-1135, 1986.

Takayasu M, Kelland DR, Minervini JV, Friedlaender FJ, Ash SR. Feasibility of direct magnetic separation of white cells and plasma from whole blood. SNMS Proceedings (3rd International Symposium on New Magneto-Science), 475-483, November 1999.

Bem DS, Sherman JD, Ash SR, Marte JC, Willis RR, Braun R, Muldoon BS. Ammonium removal with a novel zirconium silicate. ASAIO J 47:151, 2001.

Ash S. Interventional techniques in nephrology. Peritoneal Dialysis Today 6(1):10, 2001.

Ash SR. Overview of diagnostic and interventional techniques in nephrology. Hemodialysis Today 3(1):16-17, 2001.

Textbook Chapters

Ash SR. Principles and practice of hemodialysis therapy. In: Feinberg BN, ed. CRC Handbook of Clinical Engineering. (Vol. 1.) Boca Raton, FL: CRC Press, 1980;177-210.

Thornhill JA and Ash SR. Current status of hemodialysis in veterinary medicine and the development of the canine animal model for hemodialysis-related disorders in man. In: Ash SR and Thornhill JA, eds. Handbook of Animal Models of Renal Failure. Boca Raton, FL: CRC Press, 1985;1-37.

Ash SR, Carr DJ, Blake DE and Thornhill JA. The sorbent suspension reciprocating dialyzer for use in peritoneal dialysis. In: Maher JF and Winchester JF, eds. Frontiers in Peritoneal Dialysis. New York: Field, Rich and Associates, Inc., 1986;148-156.

Ash SR, Bungu ATJ, Regnier FE. Dependence of middle molecular clearance on protein concentration of peritoneal fluid. In: Maher JF and Winchester JF, eds. Frontiers in Peritoneal Dialysis. New York: Field, Rich and Associates, Inc. 1986;56-63.

Ash SR. Information for the public. In: von Recum AF, ed. Handbook of Biomaterials Evaluation - Scientific, Technical and Clinical Testing of Implant Materials. New York: Macmillan Publishing, 1986;593-596.

Ash SR. Peritoneal access devices and placement techniques. In: Nissenson AR and Fine RN, eds. Dialysis Therapy. (2nd edition), Philadelphia: Hanley & Belfus, 1993;23-30.

Ash SR. Peritoneal access devices. In: Daugirdas JT and Ing TS, eds. Handbook of Dialysis. (2nd edition), New York: Little, Brown and Co., 1994;274-300.

Ash SR, Nichols WK. Placement, repair and removal of chronic peritoneal catheters. In: Gokal R and Nolph KD, eds. Textbook of Peritoneal Dialysis. The Netherlands: Kluwer Academic Publishers, 1994;315-333.

Ash SR, Carr DJ, Diaz-Buxo JA. Peritoneal access devices. Hydraulic function and biocompatibility. In: Nissenson AR, Fine RN, and Gentile DE, eds. Clinical Dialysis. Norwalk, CT: Appleton & Lange, 1995;295-321.

Ash SR. Peritoneal access devices for intraperitoneal chemotherapy. In: Sugarbaker PH, ed. Peritoneal Carcinomatosis: Principles of Management. The Netherlands: Kluwer Academic Publishers, 1996;387-413.

Ash SR, Daugirdas JT. Peritoneal access devices. In: Daugirdas, Ing, Blake (eds). Handbook of Dialysis, (3rd edition) Philadelphia. Lippincott Williams & Wilkins, 2000:309-332.

Ash SR. Peritoneal access devices and placement techniques. In: Nissenson AR and Fine RN, eds. Dialysis Therapy. (3rd edition), Philadelphia. Hanley & Belfus, Inc., 2001;45-50.

Ash SR. Peritoneal access and its complications. IN. Horl WH, Koch M, Lindsay RM, Ronco C, Winchester JF, eds. Replacement of Renal Function by Dialysis (5th edition) The Netherlands: Kluwer Academic Publishers, 2004;231-257.

Ash SR. Peritoneal Access Devices and Placement Techniques. In: Nissenson, AR, Fine RN, eds. Handbook of Dialysis Therapy. 4th Ed. 2008. 111-135.